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Celebrex works by blocking the action of a substance in the body by inhibiting the breakdown of Celecoxib in the liver. Celebrex recently became the only drug federally approved for reducing the number of polyps in patients with familial adenomatous polyposis. Celebrex works by blocking the action of a substance in the body called cyclo-oxygenase. This medication helps you perform more of your normal daily activities. This medication should not be used if you have certain medical conditions.

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