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Gabapentin works by stabilizing electrical activity in the brain. Gabapentin works by stabilizing electrical activity in the brain. Gabapentin seems to be effective in reducing pain and spasticity in multiple sclerosis. There are alternate methods to help reduce pain that may be helpful for control of long-term pain. Gabapentin is sometimes effectiveness for patients who have failed to respond to antidepressants or mood stabilizers. Gabapentin is widely used to treat seizures associated with epilepsy.

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